Molecular Mechanisms of Cancer Biology

Understanding the molecular mechanisms involved in the development and biological activity of cancer cells is a burgeoning area of current research.  Cancer Genome and other high content data projects are revealing new proteins for study at the molecular level in cancer cells and also as new drug targets.

You will therefore develop a research profile exploiting advances in cancer genomic technologies at the level of individual proteins and protein complexes as well as being able to study them in complex biological pathways in cancer cells. A proven record of achievement in international quality publications is essential to contribute to the University’s ambition to excel at REF2020. You will also be expected to attract research income on an individual and collaborative basis with colleagues in the School of Molecular and Cellular Biology, Faculty of Medicine and Health and Astbury Centre of Structural Molecular Biology.

In addition, you will provide research supervision and attract research students to the University and undertake a teaching load deemed appropriate by the Head of School, which will be significantly reduced in the first years of the fellowship. Excellent facilities and infrastructure are available for structural molecular biology analysis (protein crystallography, NMR, mass spectrometry and protein interaction techniques), in addition to cell-based imaging, including confocal, super-resolution and electron microscopy. Moreover, high content screening facilities are available through the BioScreening Technology (adhirons, siRNAs) and Medicinal Chemistry (small molecule) groups.

You should also have a strong research background in cellular biology, structural molecular biology or protein biochemistry in the area of proteins involved in cancer.  Individuals with experience of attracting external funding are particularly encouraged to apply.

University Grade 8 (£38,511 to £45,954)

For informal enquiries about the role please contact either Professor Adrian Whitehouse, Director of Research, School of Molecular and Cellular Biology, tel: +44 (0)113 343 7096, email: or Professor David Westhead, Head of School, Molecular and Cellular Biology, tel: +44 (0)113 343 3116, email:

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